Epidemiological Characteristics of Human Papillomavirus (HPV) Infection in Different Groups of Women in Chongqing, China

Persistent high-risk (HR) human papillomavirus (HPV) infection is an essential risk factor for cervical carcinoma and precancerous lesion. There are differences in HPV distribution among different countries, regions ethnic groups. The aim of this research was to reveal the epidemiological characteristics Chongqing, China. In study, 13,788 women aged 18 78 were screened 23 genotypes by PCR-reverse dot blot hybridization. total HPV-positive rate 19.9% (2,745/13,788), while positive rates HR, low-risk (LR) 17.3% (2,379/13,788), 4.6% (638/13,788), respectively. addition cancer (CC) intraepithelial neoplasia (CIN) patients, infertile with gynecological diseases markedly higher than that healthy women. HR-HPV age groups showed statistically significant differences, prevalence peaks observed under 20 years over 50 age. Overall, HPV-52, HPV-16 HPV-58 ranked as top 3 most common subtypes Chongqing. results provide information regarding These data constitute valuable evidence prevention management development vaccines.